Get Informed | Real Stories About Prescription Opioids | Rx Awareness (2024)

In addition to the serious risks of addiction, abuse, and overdose, the use of prescription opioids can have a number of side effects, even when taken as directed:

• Tolerance—meaning you might need to take more of the medication for the same pain relief
• Physical dependence—meaning you have symptoms of withdrawal when the medication is stopped
• Increased sensitivity to pain
• Constipation
• Nausea, vomiting, and dry mouth
• Sleepiness and dizziness
• Confusion
• Depression
• Low levels of testosterone that can result in lower sex drive, energy, and strength
• Itching and sweating

There were nearly five times the number of overdose deaths involving prescription opioids in 2021 than in 1999. In 2021, almost 21% of all U.S. opioid overdose deaths involved a prescription opioid. From 1999 to 2021, nearly 280,000 people died in the United States from a prescription opioid overdose¹. Overdose is not the only risk related to prescription opioids. Anyone who takes prescription opioids can become addicted to them.

Talk to Your Doctor

Talk to your doctor about ways tomanage your pain that do not involve prescription opioids. Some of these options may actually work better and have fewer risks and side effects. Depending on the type of pain you are experiencing, options may include:

• Acetaminophen (Tylenol^®) or ibuprofen (Advil^®)
• Cognitive behavioral therapy – a psychological, goal-directed approach in which patients learn how to modify physical, behavioral, and emotional triggers of pain and stress
• Exercise therapy, including physical therapy
• Medications for depression or for seizures
• Interventional therapies (injections)
• Exercise and weight loss
• Other therapies such as acupuncture and massage

Your health and safety are important.Start the conversation with your doctor [PDF] and work together to set pain management goals and develop a treatment plan that will help you. Follow-up if your pain is not resolving as quickly as expected.

If you are struggling, there is hope. Recovery is possible.