Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting (2024)

Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting (1)Share on Pinterest

Both hydrogen peroxide and rubbing alcohol can kill germs. Generally, you can use rubbing alcohol on the skin and some surfaces while you can only use hydrogen peroxide on surfaces.

Rubbing alcohol and hydrogen peroxide are two common household cleaners. Chances are, you’ve probably come into contact with one or both of these chemical compounds at some point.

One isn’t necessarily more effective than the other. With that said, their effectiveness can vary depending on how you use them and the types of germs you’re trying to kill.

Let’s take a closer look at the key differences between rubbing alcohol and hydrogen peroxide, as well as how to use them effectively.

About rubbing alcohol

The active ingredient in rubbing alcohol is isopropanol, also known as isopropyl alcohol. A bottle of rubbing alcohol typically contains between 60 to 80 percent isopropanol dissolved in water.

Rubbing alcohol has many uses. It’s a powerful germicide, which means it has the ability to kill a wide variety of germs, including bacteria, viruses, and fungi. Rubbing alcohol is used in healthcare settings to disinfect hands and surfaces, but can also be used as a household cleaner.

In concentrations of 70 percent or higher, isopropanol has the ability to kill the new coronavirus that causes COVID-19.

About hydrogen peroxide

Unlike isopropanol, hydrogen peroxide is not a type of alcohol. You might recognize its chemical formula, H2O2, as being similar to that of water (H2O). The difference is that hydrogen peroxide has two oxygen atoms instead of one. That one extra oxygen atom makes it a strong oxidizer.

When you buy hydrogen peroxide from a pharmacy, you’re getting a solution that contains 3 percent hydrogen peroxide dissolved in water. This formulation is strong enough to kill harmful microorganisms, including bacteria, viruses, fungi, and spores.

Like rubbing alcohol, it also has the ability to destroy SARS-CoV-2, the new coronavirus. Additionally, hydrogen peroxide has many other uses in the home.

While hydrogen peroxide makes a great disinfectant, it’s not gentle enough to be used on your skin. That’s why you won’t find it in hand sanitizer.

There’s no definitive answer as to which is better at killing germs. The effectiveness of rubbing alcohol and hydrogen peroxide varies according to:

  • the surface you’re cleaning
  • the type of germs you want to destroy
  • how quickly you want it to work

Disinfecting your skin, surfaces, and fabric

In general, rubbing alcohol is a better option for your skin. This isn’t necessarily because it’s more effective, but because hydrogen peroxide is too harsh to be used on your skin.

Both can be used effectively on hard surfaces such as doorknobs, countertops, porcelain, stainless steel, and glass. However, repeated use of either substance can affect the finish of these surfaces. It’s a good idea to check whether it’s safe to use the product before you apply it.

Rubbing alcohol can also be used to disinfect some fabrics, but you’ll want to avoid using it on anything that’s synthetic or delicate. Using hydrogen peroxide on fabrics can cause yellowing.

The germs they kill

Both rubbing alcohol and hydrogen peroxide have the ability to kill many types of bacteria, including:

  • Acinetobacter baumannii: can cause infections in your blood, urinary tract, and lungs
  • E. coli: can lead to intestinal infection and sickness
  • Enterococcus faecalis: can lead to infections in your blood, heart lining, brain and spinal cord, urinary tract, gums, and open wounds
  • Listeria monocytogenes: usually found in contaminated foods, a listeria infection usually causes mild symptoms, but can lead to bacterial meningitis, endocarditis, and sepsis in some people
  • Pseudomonas aeruginosa: can cause many types of infections in people with weakened immune systems
  • Salmonella: a common cause of food poisoning, this bacteria affects the small intestines
  • Staphylococcus aureus: can cause food poisoning

According to a 2010 study, rubbing alcohol doesn’t eliminate C. difficile spores.

Rubbing alcohol and hydrogen peroxide are also effective at disabling many enveloped viruses, which have a fatty outer membrane. These include:

  • coronaviruses, including SARS-CoV-2
  • influenza viruses, such as H1N1
  • herpes simplex
  • Ebola
  • Zika

According to the Centers for Disease Control and Prevention (CDC), isopropanol is less effective at killing nonenveloped viruses such as hepatitis A and rotavirus. Hydrogen peroxide is also ineffective against the hepatitis A virus.

Hydrogen peroxide is reported to be most effective when it’s allowed to sit on surfaces for at least 10 minutes at room temperature. If time is of the essence, rubbing alcohol may be a better option for disinfecting surfaces.

  1. Be sure to use a rubbing alcohol product that contains at least 70 percent isopropanol. Don’t dilute rubbing alcohol with water.
  2. First, wash the surface you wish to disinfect with soap and water.
  3. Then use a wipe, towel, or spray bottle to evenly apply the rubbing alcohol to the surface.
  4. Let it sit for at least 30 seconds.
  1. Solutions of at least 3 percent hydrogen peroxide make efficient household disinfectants. Don’t dilute.
  2. As with rubbing alcohol, first wipe down the surface with soap and water.
  3. Use a spray bottle or a clean rag to apply the hydrogen peroxide to the surface.
  4. Allow the solution to sit on the surface for at least 10 minutes. You don’t need to wipe it off.

Both rubbing alcohol and hydrogen peroxide were once commonly used to clean minor wounds such as cuts and scrapes.

This is no longer recommended. While rubbing alcohol and hydrogen peroxide will kill harmful bacteria, they can be too harsh on the tissue surrounding the wound. Applying one of these substances may even make it harder for the wound to heal.

Instead, thoroughly rinse a superficial wound with running water to remove any dirt and debris. Then gently clean around the edges of the wound with mild soap to disinfect the area.

  • Don’t ingest either rubbing alcohol or hydrogen peroxide. They’re meant for external use only.
  • Avoid getting either substance in your eyes.
  • Make sure any indoor area is well ventilated when using either product.
  • Try to avoid getting hydrogen peroxide on your hands and skin, as it can cause irritation.
  • Store both products in a cool, dry place that’s out of reach of children and pets.
  • Rubbing alcohol is flammable and should be kept away from flames.
  • Both products can expire. Once expired, they might not be able to kill germs as effectively. Always check the expiration date on the product label before using.

Rubbing alcohol and hydrogen peroxide both kill most bacteria, viruses, and fungi. In general, rubbing alcohol is better at killing germs on your hands, as it’s gentler on your skin than hydrogen peroxide.

Hydrogen peroxide is most effective when it’s allowed to sit on surfaces for at least 10 minutes at room temperature. Rubbing alcohol has the ability to kill pathogens on your skin and surfaces in less time.

When sanitizing with either product, always carefully follow the instructions on the product label.

Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting (2024)

FAQs

Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting? ›

Both hydrogen peroxide and rubbing alcohol can kill germs. Generally, you can use rubbing alcohol on the skin and some surfaces while you can only use hydrogen peroxide on surfaces. Rubbing alcohol and hydrogen peroxide are two common household cleaners.

What is a better disinfectant, rubbing alcohol or hydrogen peroxide? ›

For example, isopropyl alcohol kills bacteria such as E. Coli and Staphylococcus in as little as ten seconds. Conversely, you'll find that hydrogen peroxide is effective against certain viruses and bacteria, but the disinfectant requires five minutes or more to produce a favorable effect.

Should I use rubbing alcohol or hydrogen peroxide on a cut? ›

Using hydrogen peroxide or rubbing alcohol to clean an injury can actually harm the tissue and delay healing. The best way to clean a minor wound is with cool running water and mild soap. Rinse the wound for at least five minutes to remove dirt, debris, and bacteria.

Does rubbing alcohol sanitize or disinfect? ›

It Disinfects (Most) Things

Hospitals also sometimes use alcohol towelettes to get rid of germs on small surfaces like stethoscopes, scissors, and thermometers. Experts don't recommend using rubbing alcohol to sterilize medical and surgical equipment because it can't kill bacterial spores, which can lead to infection.

What are the disadvantages of hydrogen peroxide as a disinfectant? ›

The main disadvantage is the small disinfecting and oxidising ability of hydrogen peroxide at active concentrations (tens of milligrams per litre), which are required for swimming pool disinfection. Another problem is the quick decomposition of hydrogen peroxide in water and the presence of oxygen radicals.

Why use hydrogen peroxide instead of rubbing alcohol? ›

Hydrogen peroxide is another antiseptic, or disinfectant, that kills viruses and various forms of bacteria. But it needs more time than rubbing alcohol does to kill germs. It needs up to 5 minutes to do its job.

Is alcohol the most effective disinfectant? ›

Ethyl alcohol, at concentrations of 60%–80%, is a potent virucidal agent inactivating all of the lipophilic viruses (e.g., herpes, vaccinia, and influenza virus) and many hydrophilic viruses (e.g., adenovirus, enterovirus, rhinovirus, and rotaviruses but not hepatitis A virus (HAV) 58 or poliovirus) 49.

What should you not clean with hydrogen peroxide? ›

Keep reading for more on that and other things you should never do with hydrogen peroxide.
  • Don't use it to clean deep cuts. ...
  • Don't use hydrogen peroxide without wearing gloves. ...
  • Don't mix it with vinegar. ...
  • Do not ingest it. ...
  • Don't use it if it doesn't fizz when you start cleaning.
Apr 18, 2020

When should you not use hydrogen peroxide? ›

This product works by releasing oxygen when it is applied to the affected area. The release of oxygen causes foaming, which helps to remove dead skin and clean the area.This product should not be used to treat deep wounds, animal bites, or serious burns.

Does hydrogen peroxide actually disinfect cuts? ›

While the sometimes-painful bubbling is definitely sanitizing the area, it's also destroying healthy tissue. ER physician and wound specialist Troy Madsen, MD, explains why hydrogen peroxide is such a bad idea for first aid and the best way to clean and treat a wound to keep it from getting infected.

Can I just use rubbing alcohol to sanitize? ›

Rubbing alcohol has many uses. It's a powerful germicide, which means it has the ability to kill a wide variety of germs, including bacteria, viruses, and fungi. Rubbing alcohol is used in healthcare settings to disinfect hands and surfaces, but can also be used as a household cleaner.

What kills germs better, alcohol or bleach? ›

While the relative effectiveness of alcohol and bleach on bacteria and viruses does not vary greatly, it is important not to mix the two agents during cleaning.

Why is 70 isopropyl alcohol used as disinfectant? ›

First, it has been found to be more effective at killing microorganisms than higher concentrations of isopropyl alcohol. This is because the water content in the 70% IPA solution allows for better penetration into the microorganisms and denaturation of proteins.

Is hydrogen peroxide the best disinfectant? ›

Hydrogen peroxide is incredibly effective; it cleans, disinfects, and deodorizes surfaces. It is also anti-bacterial, anti-fungal, anti-mold, and anti-mildew. This is especially useful in healthcare facilities fighting against infections and other emerging threats.

Is hydrogen peroxide a better disinfectant than vinegar? ›

Vinegar is commonly referred to as a natural disinfectant, and while it has some disinfectant properties, it is not as effective as alcohol or hydrogen peroxide at killing pathogens. The main ingredient in vinegar, acetic acid, helps to break down dirt and can reduce bacteria on dirty surfaces.

Which is a better disinfectant vinegar or hydrogen peroxide? ›

Vinegar can be used as a safer bleach alternative for some applications, like cleaning. It is also biodegradable. However, vinegar is not a registered disinfectant and does not kill dangerous bacteria like staphylococcus. Hydrogen peroxide has antimicrobial ingredients and can be an effective household cleaner.

What should you not use hydrogen peroxide for? ›

The release of oxygen causes foaming, which helps to remove dead skin and clean the area.This product should not be used to treat deep wounds, animal bites, or serious burns.

Should I put peroxide on an infected wound? ›

To help prevent this, people often douse a cut with hydrogen peroxide before applying ointment and bandage. They've been doing it for decades, in fact. But it's a practice that's no longer advised. "Hydrogen peroxide is actually detrimental to wound healing," says Dr.

What is a good natural disinfectant? ›

Hydrogen peroxide is one of the most powerful natural cleaning and disinfecting agents. Health professionals trust it against harmful bacteria, antigens, and viruses.

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