This is a prescription product. Please speak with your doctor for more information.
This is a prescription product. Please speak with your doctor for more information.
How Do I Get Upneeq?
You can be prescribed Upneeq® through dermatologists, aesthetics practices, medical spas, and all types of eye care professionals. Upneeq® is available for purchase directly at medical providers offices or through RVL Pharmacy.
If you have any questions, you can contact RVL Pharmacy at 844-RVL-EYES (844-785-3937).
How Do I Apply Upneeq?
Apply Upneeq to your affected eye(s) in 2 easy steps
 | Step 1: Cut open foil wrapper and remove single-use vial |
 | Step 2: Apply one drop of Upneeq in each affected eye as directed, once a day
|
- If you wear contact lenses, remove them before applying Upneeq eyedrops
- You may put them back in 15 minutes after applying Upneeq
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least 15 minutes between applications
Upneeq should only be used as directed
- Upneeq is designed to only be applied as an eyedrop
- Each vial contains enough Upneeq solution to allow for one drop in each affected eye
- The solution should never be swallowed or ingested in any other way
- Storage requirements: Upneeq should be stored at 68°F-77°F (20°C-25°C) and should be protected from excessive heat
- Keep out of reach of children
- For complete instructions on using Upneeq, please see the Instructions for Use section in the full Prescribing Information
844-RVL-EYES (844-785-3937)
Elevate your expectations for what prescription access should be with Upneeq
For more information about the location and hours for RVL Pharmacy, click here.
RVL Pharmacy ships to patients everywhere in the Continental U.S.
RVL Pharmacy
2500 Main Street Extension, Suite 10
Sayreville, NJ 08872
Phone: 844-RVL-EYES (844-785-3937)
Fax: 844-567-3937
Have more questions about Upneeq? Check out our FAQ section !
Patient FAQs
Get to know Upneeq a little better. Here are some commonly asked questions from patients interested in Upneeq.
What happens after my doctor writes me a prescription for Upneeq? '
Once your eye doctor sends your prescription to RVL Pharmacy, you will receive a phone call from RVL Pharmacy Call Center 844-RVL-EYES(844-785-3937). And don't worry if you miss our call; just call us back at 844-RVL-EYES(844-785-3937).
 | You will be getting a phone call from RVL Pharmacy: 844-785-3937 |
Please save our number in your phone so you recognize us when we call you shortly!
RVL Pharmacy will verify your information and process your credit card payment with you over the phone. Once your payment is processed, your Upneeq prescription will be shipped directly to your preferred address.
How long does it take for my prescription to arrive?
You should receive your prescription for Upneeq within 2 to 4 days after payment.
Does RVL Pharmacy accept insurance?
RVL Pharmacy does not accept payments from insurance providers. Upneeq is available directly to patients through a fully transparent pricing model outside of the insurance process.
Does my insurance pay for an Upneeq prescription?
RVL Pharmacy does not accept payments from insurance providers. Upneeq is priced transparently and consistently for all patients.
Can I track my Upneeq prescription once it's shipped?
Yes. You will be sent a tracking number when Upneeq has shipped from RVL Pharmacy or KnippeRx. If you have any questions, call 844-RVL EYES (844-785-3937).
Patient Resources
Here are some additional resources that you may find useful.
 | Patient Education Brochure You can meet Upneeq through this downloadable brochure. Learn more about what Upneeq can do, and how it is applied as a once-daily treatment. |
 | Interactive Eye Assessment If your eyes are looking a little tired, use this quick interactive tool to assess your eyelid(s). Be sure to share your results with your eye doctor during your next visit. |
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IMPORTANT SAFETY INFORMATION
What is UPNEEQ?
UPNEEQ ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat acquired blepharoptosis (low-lying lids) in adults.
What warnings and precautions are associated with UPNEEQ?
- Low-lying lids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Tell your doctor if you have any of these conditions.
- UPNEEQ is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
- Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking UPNEEQ. Call your doctor immediately if you feel your symptoms may be getting worse.
- UPNEEQ may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using UPNEEQ.
- Do not let the tip of the UPNEEQ vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each UPNEEQ vial is for one-time use and should be discarded after being used.
What are the most common side effects of UPNEEQ?
The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.
What should my doctor know about before prescribing me UPNEEQ?
- Your doctor should review your full medical history before prescribing UPNEEQ.
- UPNEEQ belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use UPNEEQ carefully if you currently take an alpha-adrenergic agonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.
- Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using UPNEEQ, as it may affect the way your body absorbs the medication.
These are not all of the possible side effects of UPNEEQ. Tell your doctor if you have any side effect that bothers you or does not go away. Call your doctor for medical advice about side effects.
To report side effects or product complaints, contact RVL Pharmaceuticals at 1-877-482-3788. You may also report side effects to the FDA by calling 1-800-FDA-1088 or visit www.fda.gov/medwatch.
This is a summary of the most important safety information for UPNEEQ. For more in-depth safety information, please review the full PrescribingInformation for UPNEEQ.
