Generic Upneeq Availability - Drugs.com (2024)

Last updated on Mar 6, 2024.

Upneeq is a brand name of oxymetazoline ophthalmic, approved by the FDA in the following formulation(s):

UPNEEQ (oxymetazoline hydrochloride - solution/drops;ophthalmic)

  • Manufacturer: RVL PHARMS
    Approval date: July 8, 2020
    Strength(s): 0.1% [RLD]

Has a generic version of Upneeq been approved?

No. There is currently no therapeutically equivalent version of Upneeq available in the United States.

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Upneeq. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: Generic Drug FAQ.

Related patents

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

  • Compositions and methods for treating ocular disorders
    Patent 10,799,481
    Issued: October 13, 2020
    Inventor(s): deVries Tina & Jacobs David
    Assignee(s): RVL PHARMACEUTICALS, INC.

    The present disclosure is directed to compositions comprising oxymetazoline and methods of treating various eye disorders related to drooping eyelids, such as ptosis, in a subject comprising administering to the subject compositions comprising oxymetazoline.

    Patent expiration dates:

    • December 16, 2039

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Oxymetazoline compositions
    Patent 10,814,001
    Issued: October 27, 2020
    Inventor(s): deVries Tina & Jacobs David
    Assignee(s): RVL Pharmaceuticals, Inc.

    The present disclosure is directed to compositions comprising oxymetazoline and methods of stabilizing oxymetazoline compositions for long term storage.

    Patent expiration dates:

  • Oxymetazoline compositions
    Patent 10,898,573
    Issued: January 26, 2021
    Inventor(s): deVries Tina & Jacobs David
    Assignee(s): RVL Pharmaceuticals, Inc.

    The present disclosure is directed to compositions comprising oxymetazoline and methods of stabilizing oxymetazoline compositions for long term storage.

    Patent expiration dates:

    • December 16, 2039

      Drug product

  • Compositions and methods for non-surgical treatment of ptosis
    Patent 10,912,765
    Issued: February 9, 2021
    Inventor(s): Silverberg Mark
    Assignee(s): VOOM, LLC

    Provided are pharmaceutical compositions, and methods of use of the compositions, for the non-surgical treatment of ptosis (eyelid droop). In one embodiment the composition includes oxymetazoline 0.1% formulated for topical administration to an eye. In one embodiment the composition includes a synergistic combination of oxymetazoline and phenylephrine, formulated for topical administration to an eye. Oxymetazoline alone causes no pupillary dilation (mydriasis), and a synergistic combination of oxymetazoline and phenylephrine induces no clinically significant mydriasis. In addition to providing desirable cosmetic effects, the compositions and methods of the invention can improve visual fields otherwise compromised by ptosis.

    Patent expiration dates:

    • August 26, 2031

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Compositions and methods for treating ocular disorders
    Patent 10,940,138
    Issued: March 9, 2021
    Inventor(s): deVries Tina & Jacobs David
    Assignee(s): RVL Pharmaceuticals, Inc.

    The present disclosure is directed to compositions comprising oxymetazoline and methods of treating various eye disorders related to drooping eyelids, such as ptosis, in a subject comprising administering to the subject compositions comprising oxymetazoline.

    Patent expiration dates:

    • December 16, 2039

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Oxymetazoline compositions
    Patent 11,103,482
    Issued: August 31, 2021
    Inventor(s): deVries Tina & Jacobs David
    Assignee(s): RVL Pharmaceuticals, Inc.

    The present disclosure is directed to compositions comprising oxymetazoline and methods of stabilizing oxymetazoline compositions for long term storage.

    Patent expiration dates:

    • December 16, 2039

      Drug product

  • Patent 11,311,515

    Patent expiration dates:

    • December 16, 2039

      Drug product

  • Patent 11,324,722

    Patent expiration dates:

    • December 16, 2039

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Patent 11,541,036

    Patent expiration dates:

    • December 16, 2039

      Drug product

  • Patent 11,701,343

    Patent expiration dates:

    • December 16, 2039

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Compositions and methods for non-surgical treatment of ptosis
    Patent 8,357,714
    Issued: January 22, 2013
    Inventor(s): Silverberg Mark
    Assignee(s): Voom, LLC

    Provided are pharmaceutical compositions, and methods of use of the compositions, for the non-surgical treatment of ptosis (eyelid droop). In one embodiment the composition includes oxymetazoline 0.1% formulated for topical administration to an eye. In one embodiment the composition includes a synergistic combination of oxymetazoline and phenylephrine, formulated for topical administration to an eye. Oxymetazoline alone causes no pupillary dilation (mydriasis), and a synergistic combination of oxymetazoline and phenylephrine induces no clinically significant mydriasis. In addition to providing desirable cosmetic effects, the compositions and methods of the invention can improve visual fields otherwise compromised by ptosis.

    Patent expiration dates:

    • August 26, 2031

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

  • Compositions and methods for non-surgical treatment of Ptosis
    Patent 9,867,808
    Issued: January 16, 2018
    Inventor(s): Silverberg Mark
    Assignee(s): VOOM, LLC

    Provided are pharmaceutical compositions, and methods of use of the compositions, for the non-surgical treatment of ptosis (eyelid droop). In one embodiment the composition includes oxymetazoline 0.1% formulated for topical administration to an eye. In one embodiment the composition includes a synergistic combination of oxymetazoline and phenylephrine, formulated for topical administration to an eye. Oxymetazoline alone causes no pupillary dilation (mydriasis), and a synergistic combination of oxymetazoline and phenylephrine induces no clinically significant mydriasis. In addition to providing desirable cosmetic effects, the compositions and methods of the invention can improve visual fields otherwise compromised by ptosis.

    Patent expiration dates:

    • August 26, 2031

      Patent use: METHOD OF TREATING BLEPHAROPTOSIS

More about Upneeq (oxymetazoline ophthalmic)

  • Check interactions
  • Compare alternatives
  • Reviews (16)
  • Side effects
  • Dosage information
  • FDA approval history
  • Breastfeeding
  • En español

Patient resources

  • Upneeq drug information
  • Upneeq (Advanced Reading)

Other brands

Visine L.R. Long Lasting Redness Relief, OcuClear

Professional resources

  • Upneeq prescribing information
  • Oxymetazoline (AHFS Monograph)

Other brands

Visine L.R. Long Lasting Redness Relief

Related treatment guides

  • Blepharoptosis

Glossary

TermDefinition
Drug PatentA drug patent is assigned by the U.S. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation.
Drug ExclusivityExclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circ*mstance of the exclusivity grant.
RLDA Reference Listed Drug (RLD) is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

Generic Upneeq Availability - Drugs.com (2024)

FAQs

Is there a generic version of Upneeq? ›

Specifically, Upneeq is approved by the Food and Drug Administration (FDA) to treat droopy eyelids in adults. It's not available in a generic version.

How much is Upneeq without insurance? ›

The cost for Upneeq ophthalmic solution 0.1% is around $229 for a supply of 30 solution, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans.

Can you get a sample of upneeq? ›

Welcome to the UPNEEQ (oxymetazoline hydrochloride ophthalmic solution), 1% E-Sampling Portal where you can request UPNEEQ samples at your convenience. The sample allocation is customized specifically to your patient treatment needs and is based on your UPNEEQ patient starts.

Can I use expired upneeq? ›

Keep this medication in the original container. Throw away any unused medication after the expiration date.

Is Lumify the same as Upneeq? ›

For example, Upneeq is a prescription eye solution that treats droopy eyelids in adults. You'll need to visit an eye doctor, dermatologist, or other healthcare professional to get a prescription for Upneeq. Lumify treats minor eye redness.

What over the counter eyedrops are good for droopy eyelids? ›

Upneeq (oxymetazoline) is an alpha-1 receptor agonist. It's an eye drop used to treat droopy eyelids (acquired blepharoptosis) in people ages 13 years and older. The typical dose of Upneeq (oxymetazoline) is one drop in the affect eye(s) once per day.

Will Medicare pay for Upneeq? ›

In general, Medicare prescription drug plans (Part D) do not cover this drug. Be sure to contact your specific plan to verify coverage information.

Do you have to use Upneeq forever? ›

Even though the results are not permanent, you can continue to use Upneeq indefinitely. If you have droopy eyelids and want younger-looking eyes without surgical intervention, a Upneeq before and after transformation may be right for you.

Can you use 2 drops of Upneeq? ›

You'll apply one drop of Upneeq to one or both eyes (as directed by your doctor) once daily. Be careful that the eyedrop container does not touch your eye. If you wear contact lenses, remove them before applying Upneeq. Then wait at least 15 minutes before reinserting them.

What are the negative side effects of Upneeq? ›

What are the most common side effects of Upneeq?
  • Eye tearing, redness, or discomfort.
  • Dry eye.
  • Blurred vision.
  • Pain after applying the eye drops.
  • Eye irritation.
  • Headache.
May 9, 2024

Does insurance cover Upneeq? ›

Does Insurance Cover Upneeq? Upneeq isn't considered a medically necessary treatment when used for cosmetic reasons, so health insurance doesn't cover the cost of the prescription.

Does Upneeq work on hooded eyelids? ›

Upneeq is ideal for people who have droopy or low-lying eyelids caused by mild, moderate, or severe eyelid ptosis.

What is similar to Upneeq? ›

Oxymetazoline ophthalmic Alternatives Compared
Oxymetazoline ophthalmicLumify (brimonidine)Fluorometholone ophthalmic
Brand Names
Upneeq, Visine L.R. Long Lasting Redness ReliefOther brimonidine brands include: Alphagan P, Lumify Preservative Free, QolianaEflone, Flarex, FML, FML Forte Liquifilm, FML Liquifilm, FML S.O.P.
41 more rows

Who cannot use Upneeq? ›

Use UPNEEQ carefully if you currently take an alpha-adrenergic antagonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.

What happens if you use 2 year expired eye drops? ›

Furthermore, expired eye drops may produce uncomfortable side effects, such as itching, blurred vision, burning, and redness. Another risk of using expired eye drops is that they may become contaminated with bacteria or fungi, leading to an eye infection.

What product is similar to Upneeq? ›

Upneeq Alternatives Compared
Upneeq (oxymetazoline)Oxymetazoline ophthalmic
Dosage Form(s) Available
Ophthalmic solutionN/A
Brand Names
Other oxymetazoline brands include: Visine L.R. Long Lasting Redness ReliefUpneeq, Visine L.R. Long Lasting Redness Relief
39 more rows

Is Afrin the same as Upneeq? ›

Upneeq contains the same ingredient as Afrin, which is not safe for long term use, but Upneeq can be used indefinitely.

Will insurance pay for Upneeq eye drops? ›

Does Insurance Cover Upneeq? Upneeq isn't considered a medically necessary treatment when used for cosmetic reasons, so health insurance doesn't cover the cost of the prescription.

Who should not use Upneeq? ›

Use UPNEEQ carefully if you currently take an alpha-adrenergic antagonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.

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