Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist (2024)

Ashley Abramson

Ashley Abramson

Ashley Abramson is a writer-mom hybrid. Her work, mostly focused on health, psychology, and parenting, has been featured in the Washington Post, New York Times, Allure, and more. She lives in the Milwaukee suburbs with her husband and two young sons.

Follow

updated Nov 1, 2022

We independently select these products—if you buy from one of our links, we may earn a commission. All prices were accurate at the time of publishing.

Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist (1)

SavePin ItSee More Images

When you’re worried about getting sick, it’s natural to bring out the big guns, like bleach or rubbing alcohol. Both of these products are effective at disinfecting your surfaces, but did you know there’s a counter-intuitive rule of thumb to follow when you clean with alcohol? It has to do with the percentage of alcohol by volume.

You would think alcohol solutions with a higher percentage would be more powerful at killing germs on your high-touch items like phones and doorknobs, right? A lower percent alcohol means there’s more water diluting the mix in the bottle. But according to microbiology, 70 percent alcohol is probably more effective than 91 percent for disinfecting—depending on what kind of germs you’re trying to kill.

Here’s why lower-percentage alcohol might be a better weapon against germs:

According to Dr. Elizabeth Scott, professor of microbiology at Simmons Center for Hygiene and Health in Home and Community at Simmons University in Boston, higher-percentage alcohols are more concentrated. That means lower percentages, like 70 percent, have more water in them. Turns out, the water is actually an important ingredient here.

SavePin ItSee More Images

Basically, a 90 or 91 percent alcohol solution is too powerful in some cases: It fries the outside of the cell before it can get into the inside and kill the actual germ. 70 percent alcohol is just the right proportion of water and alcohol to zap the entire cell.

“Seventy percent alcohol has some water in it that allows it to cross a cell membrane, to really get into the bacteria to kill them,” Scott says.

Interestingly, Scott explains this rule of thumb only applies when you’re attempting to fend off bacteria. Alcohol’s effectiveness against viruses depends on the unique virus.

Viruses with an envelope structure — including the flu virus, the common cold, HIV, and SARS-CoV-2 (the virus that causes COVID-19) — can be deactivated by alcohol solutions (like hand sanitizer) of 60 percent or more, while others like norovirus won’t be effectively targeted by any concentration of alcohol. (Hand-washing helps to physically remove every type of virus and bacteria from your hands and is an important part of any hygiene routine.)

Practically, how does this rule of thumb apply to home hygiene? If you’re cutting raw chicken on the counter and want to effectively disinfect the surface to prevent cross-contamination of E. coli and salmonella bacteria, you’d want to opt for 70 percent alcohol. But if you’re trying to disinfect a surface that might have viruses lingering on it — for example, if someone in your house has the flu — any dilution of alcohol will work as long as it’s above the recommended 60 percent.

In any case, it’s important to focus on hygiene practices like thorough hand washing (20 seconds of scrubbing each time!) and targeted hygiene (regularly disinfecting high-traffic hand-contact areas in your home, especially if someone sick has touched them). Stay healthy!

Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist (2024)

FAQs

Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist? ›

Basically, a 90 or 91 percent alcohol solution is too powerful in some cases: It fries the outside of the cell before it can get into the inside and kill the actual germ. 70 percent alcohol is just the right proportion of water and alcohol to zap the entire cell.

Why is 70% alcohol used for disinfection rather than 90% concentration of alcohol? ›

70% IPA solutions penetrate the cell wall more completely which permeates the entire cell, coagulates all proteins, and therefore the microorganism dies. Extra water content slows evaporation, therefore increasing surface contact time and enhancing effectiveness.

Why is 70 alcohol better than 90? ›

Even though you may think the higher concentration is more effective, experts say 70% is actually better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria. The disinfecting power of rubbing alcohol drops at concentrations higher than 80%-85%.

Why is 70% alcohol was used in microbiology? ›

First, it has been found to be more effective at killing microorganisms than higher concentrations of isopropyl alcohol. This is because the water content in the 70% IPA solution allows for better penetration into the microorganisms and denaturation of proteins.

Why is 70% ethanol more effective as an disinfectant than 100% ethanol Please include references? ›

At a 70% concentration, however, the ethanol takes longer to evaporate and this longer contact time means that it is able to penetrate cells more effectively. The water in a 70% grade is also important in denaturing proteins. And 70% ethanol also tends to be cheaper and is less flammable [1].

What is the difference between 70 and 91 isopropyl alcohol? ›

70% IPA solutions are very effective in breaching the cell wall fully. Also, the presence of water slows down evaporation and increases the surface contact time with the membrane. With 91% IPA, the evaporation is instant and protein coagulates, rendering the effect of the IPA greatly reduced.

Is 91 percent alcohol good for disinfecting? ›

The Centers for Disease Control and Prevention (CDC) recommends an alcohol concentration of between 60 and 90 percent for disinfection purposes.

Top Articles
Latest Posts
Article information

Author: Wyatt Volkman LLD

Last Updated:

Views: 6523

Rating: 4.6 / 5 (46 voted)

Reviews: 85% of readers found this page helpful

Author information

Name: Wyatt Volkman LLD

Birthday: 1992-02-16

Address: Suite 851 78549 Lubowitz Well, Wardside, TX 98080-8615

Phone: +67618977178100

Job: Manufacturing Director

Hobby: Running, Mountaineering, Inline skating, Writing, Baton twirling, Computer programming, Stone skipping

Introduction: My name is Wyatt Volkman LLD, I am a handsome, rich, comfortable, lively, zealous, graceful, gifted person who loves writing and wants to share my knowledge and understanding with you.